Portal:Spaceflight/On This Day/22 January
- 1965 - A Delta C launches the Tiros 9 weather satellite
- 1966 - A Vostok-2 rocket launches a Zenit-2 spy satellite
- 1968 - A Saturn IB launches Apollo 5, an unmanned test of the Apollo Lunar Module
- 1969 - A Delta C launches the OSO scientific satellite
- 1969 - A Titan IIIB launches a KH-8 spy satellite
- 1975 - A Delta 2910 launches the Landsat 2 Earth resources satellite
- 1976 - A Molniya-M launches a Molniya-1 communication satellite
- 1976 - A Kosmos-3M launches a Tselina-O spy satellite
- 1987 - A Kosmos-3M launches a Taifun-2 calibration satellite
- 1987 - A Molniya-M launches a Molniya-3 communication satellite
- 1990 - An Ariane 4 (40) launches the SPOT 2 remote sensing spacecraft, and six Oscar amateur radio satellites.
- 1992 - Space Shuttle Discovery launches on mission STS-42.
- 1997 - Space Shuttle Atlantis lands at the Kennedy Space Center after mission STS-81 to Mir.
- 1998 - A Shavit-1 fails to launch the Ofek-4 spy satellite, due to a second stage malfunction.
- 2003 - NASA receives the last transmission from the Pioneer 10 spacecraft, the farthest man-made object from Earth.
- 2011 - An H-IIB rocket launches JAXA's Kounotori 2 cargo spacecraft to the International Space Station.